A Transition in Brain State during Propofol-Induced Unconsciousness
نویسندگان
چکیده
منابع مشابه
A transition in brain state during propofol-induced unconsciousness.
Rhythmic oscillations shape cortical dynamics during active behavior, sleep, and general anesthesia. Cross-frequency phase-amplitude coupling is a prominent feature of cortical oscillations, but its role in organizing conscious and unconscious brain states is poorly understood. Using high-density EEG and intracranial electrocorticography during gradual induction of propofol general anesthesia i...
متن کاملThalamocortical synchronization during induction and emergence from propofol-induced unconsciousness.
General anesthesia (GA) is a reversible drug-induced state of altered arousal required for more than 60,000 surgical procedures each day in the United States alone. Sedation and unconsciousness under GA are associated with stereotyped electrophysiological oscillations that are thought to reflect profound disruptions of activity in neuronal circuits that mediate awareness and cognition. Computat...
متن کاملDynamic Repertoire of Intrinsic Brain States Is Reduced in Propofol-Induced Unconsciousness
The richness of conscious experience is thought to scale with the size of the repertoire of causal brain states, and it may be diminished in anesthesia. We estimated the state repertoire from dynamic analysis of intrinsic functional brain networks in conscious sedated and unconscious anesthetized rats. Functional resonance images were obtained from 30-min whole-brain resting-state blood oxygen ...
متن کاملReconfiguration of network hub structure after propofol-induced unconsciousness.
INTRODUCTION General anesthesia induces unconsciousness along with functional changes in brain networks. Considering the essential role of hub structures for efficient information transmission, the authors hypothesized that anesthetics have an effect on the hub structure of functional brain networks. METHODS Graph theoretical network analysis was carried out to study the network properties of...
متن کاملAuditory processing during deep propofol sedation and recovery from unconsciousness.
OBJECTIVE Using evoked potentials, this study investigated effects of deep propofol sedation, and effects of recovery from unconsciousness, on the processing of auditory information with stimuli suited to elicit a physical MMN, and a (music-syntactic) ERAN. METHODS Levels of sedation were assessed using the Bispectral Index (BIS) and the Modified Observer's Assessment of Alertness and Sedatio...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2014
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5813-12.2014